53. Isolation, Structure, and Reactivity of an Arylnickel(II) Pivalate Complex in Catalytic C–H/C–O Biaryl Coupling
Muto, K.; Yamaguchi, J.; Lei, A.; Itami, K.
J. Am. Chem. Soc. 2013, 135, 16384–16387.
DOI: 10.1021/ja409803x

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52. Palladium-Catalyzed C–H and C–N Arylation of Aminothiazoles with Arylboronic Acids

Uehara, T. N.; Yamaguchi, J.; Itami, K.
Asian J. Org. Chem. 20132,1973–2013.
DOI: 10.1002/ajoc.201300172
Highlights Chemistry Views. Mukaiyama Aldol Issue.  Most Accessed Paper (No.1 in November 2013).

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51. Biaryl Synthesis through Metal-Catalyzed C–H Arylation
Yamaguchi, J*; Itami, K.*
“Metal-Catalyzed Cross-Coupling Reactions and More”, 2013, Wiley-VCH
DOI: 10.1002/9783527655588.ch17

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50. C–H Alkenylation of Azoles with Enols and Esters by Nickel Catalysis Acids

Lingkui, M.; Kamada, Y.; Muto, K.; Yamaguchi, J.; Itami, K.
Angew. Chem., Int. Ed. 2013, 52, 38, 10048­–10051.
DOI: 10.1002/anie.201304492
Highlights Newspapers (Chunichi, The Chemical Daily, Yahoo! News)

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49. Aromatic C–H Coupling with Hindered Arylboronic Acids by Pd/Fe Dual Catalysts
Yamaguchi, K.; Kondo, H.; Yamaguchi, J.; Itami, K.
Chem. Sci. 2013, 3753–3757.
DOI: 10.1039/C3SC51206A
Highlights Most Accessed Articles (June 2013)

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48. Synthesis of Thiophene-Based TAK-779 Analogues by C–H Arylation
Junker, A.; Yamaguchi, J.; Itami, K.; Wünsch, B.
J. Org. Chem. 201378, 5579–5586.
DOI: 10.1021/jo400692p

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47. Nickel-Catalyzed Direct Coupling of Heteroarenes
Yamaguchi, J.; Muto, K.; Amaike, K.; Yamamoto, T.; Itami, K.

J. Synth. Org. Chem. Jpn. 201371, 576­­–587.
DOI: 10.5059/yukigoseikyokaishi.71.576

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46. Decarbonylative C–H Biaryl Coupling
Yamaguchi, J.; Itami, K.
Kagaku 2013, 35–39.

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45. Recent Progress in Nickel-Catalyzed Biaryl Coupling
Yamaguchi, J.; Muto, K.; Itami, K.
Eur. J. Org. Chem. 2013, 19–30.
DOI:10.1002/ejoc.201200914
Highlights Most Accessed Articles (January 2013)

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44. Improvement of σ1 receptor affinity by late-stage C–H bond arylation of spiro cyclic lactones
Meyer, C.; Neue, B.; Schepmann, D.; Yanagisawa, S.; Yamaguchi, J.; Würthwein, E.-U.; Itami, K.*; Wünsch, B.*
Bioorg. Med. Chem. 201321, 1844–1856.
DOI:10.1016/j.bmc.2013.01.038

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43. 炭素‒水素結合直接変換をとする生物活性物質の合成-直感的に分子をつなげる新手法
Yamaguchi, J.
化学と工業 2012, 65, 952.

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42. Pd-catalyzed direct C–H bond functionalization of spirocyclic sigma-1 ligands: generation of a pharmacophore model and analysis of reverse binding mode by docking into a 3D homology model of the sigma-1 receptor

Meyer, C.; Schepmann, D.; Yanagisawa, S.; Yamaguchi, J.; Dal Col, V.; Laurini, E.; Itami, K.*; Pricl, S.; Wünsch, B.*
J, Med. Chem. 201255, 8047–8065.
DOI:10.1021/jm300894h

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41. Decarbonylative C–H Coupling of Azoles and Aryl Esters: Unprecedented Nickel Catalysis and Application to the Synthesis of Muscoride A
Amaike, K.; Muto, K.; Yamaguchi, J.; Itami, K.
J. Am. Chem. Soc.2012134, 13573–13576.
DOI:10.1021/ja306062c
Highlights Newspapers (Chu-nichi, Asahi, The Chemical Daily, Yahoo!News, Mynavi-News, Nikkan kogyo, Kagaku Shinbun), Most Read Articles in August 2012

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40. Late-Stage C–H Bond Arylation of Spirocyclic sigma-1 Ligands for Analysis of Complementary sigma-1 Receptor Surface
Meyer, C.; Schepmann, D.; Yanagisawa, S.; Yamaguchi, J.; Wünsch, B.; Itami, K.*
Eur. J. Org. Chem. 2012, 5972–5979.
DOI:10.1002/ejoc.201200837

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39. Synthesis of Bioactive Compounds through C–H Bond Functionalization
Yamaguchi, J.; Itami, K.
Fine Chemicals 2012, 41, 38­–44.
[LINK]

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38. Pd- and Cu-catalyzed C–H Arylation of Indazoles
Hattori, K.; Yamaguchi, K.; Yamaguchi, J.; Itami, K.
Tetrahedron (Special Issue) 2012, 68, 7605–7612.
DOI:10.1016/j.tet.2012.05.091

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37. Hindered Biaryls by C–H Coupling: Bisoxazoline-Pd Catalysis Leading to Enantioselective C-H Coupling
Yamaguchi, K.; Yamaguchi, J.; Studer, A.; Itami, K.
Chem. Sci. 2012, 7, 2165–2169.
DOI:10.1039/C2SC20277H
Highlights RSC Chemical Science blog, Most Read Articles in March and April 2012

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36. Mechanistic Studies on the Pd-catalyzed Direct C¿H Arylation of 2-Substituted Thiophene Derivatives with Arylpalladium Bipyridyl Complexes
Steinmetz, M.; Ueda, K.; Grimme, S.; Yamaguchi, J.; Kirchberg, S.; Itami, K.*; Studer, A.*
Chem. Asian J. 2012, 7, 1256–1260.
DOI: 10.1002/asia.201101011

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35. Nickel-Catalyzed C−H/C−O Coupling of Azoles with Phenol Derivatives
Muto, K.; Yamaguchi, J.; Itami, K.
J. Am. Chem. Soc. 2012134, 169–172.
DOI:10.1021/ja210249h
Highlights Newspapers (Yomiuri, Chu-nichi, The Chemical Daily, Yahoo!News, NanotechJapan Nikkan kogyo, Kagaku Shinbun), Most Read Articles (January, 2012), Highlighted as a “SynStory” article in SYNFORM (April 2012), Highlighted in Chemical Engineering (Feb 2012)

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34. C–H Bond Functionalization: Emerging Synthetic Tools for the Synthesis of Natural Products and Pharmaceuticals
Yamaguchi J.; Yamaguchi, A. D.; Itami, K.
Angew. Chem., Int. Ed­. 2012, 51, 8960–9009
DOI:10.1002/anie.201201666
Highlights Chemistry Views. Most Accessed Articles (2011–2013). Selected as the Cover of the Issue.

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