Seminar, Feb, 26th, 2019: Prof. Shaolin Zhu [Nanjing Univ]

Abstract:

A major area of research focus in the Zhu lab is NiH-catalyzed remote functionalization chemistry. By synergistic combination of NiH-catalyzed alkene isomerization and nickel-catalyzed cross-coupling chemistry, they have developed remote C(sp³)–H arylation, alkylation, amination, and thiolation with divergent site-selectivities as well as asymmetric tranformations.

Short Biography

Shaolin Zhu received his B. S. from Nanjing University in 2005. He conducted his graduate studies at SIOC under the mentorship of Prof. Dawei Ma. His graduate studies focused on the synthesis of Tamiflu. In 2010, Shaolin joined the group of Prof. David W. C. MacMillan at Princeton as a postdoctoral associate where he explored the copper chemistry. Then he moved to Boston in 2013 and joined Buchwald group at MIT as a postdoctoral fellow where he developed the CuH-catalyzed hydroamination chemistry. In September 2015, Shaolin joined the Department of Chemistry at Nanjing University, where his group’s work has focused primarily on asymmetric catalysis and organic synthesis.

References

[1] F. Zhou, Y. Zhang, X. Xu, S. Zhu. Angew. Chem. Int. Ed., 58, 1754–1758 (2019).

[2] J. Xiao, Y. He, F. Ye, S. Zhu. Chem, 4, 1645–1657 (2018).

[3] F. Zhou, J. Zhu, Y. Zhang, S. Zhu. Angew. Chem. Int. Ed., 57, 4058–4062 (2018).

[4] F. Chen, K. Chen, Y. Zhang, Y. He, Y.-M. Wang, S. Zhu. J. Am. Chem. Soc., 139, 13929–13935 (2017).

[5] Y. He, Y. Cai, S. Zhu. J. Am. Chem. Soc., 139, 1061–1064 (2017).