Highlights
• We successfully synthesized complex “polycyclic structures”*—commonly found in natural products and pharmaceuticals—in just a single reaction step.
• Using a “one-pot synthesis”* and “multicomponent reaction”* that combines three simple starting materials, complex frameworks can be efficiently constructed.
• We developed a new method that generates and utilizes the highly reactive intermediate o-quinodimethane* on demand during the reaction.
• This approach offers broad potential applications in synthetic chemistry, drug discovery, and functional materials.
Building molecules
分子をつなぐ。