博士論文

芳香族カルボニル化合物の触媒的変換反応: 脱カルボニル型カップリング反応/芳香環交換反応/脱アシル型カップリング反応

Catalytic Transformations of Aromatic Carbonyl Compounds: Decarbonylative Couplings/Aryl Exchange Reactions/Deacylative Couplings

研究業績

85. Decarbonylative Diaryl Ether Synthesis by Pd and Ni Catalysis

Takise, R.; Isshiki, R. Muto K.; Itami, K.; Yamaguchi, J.
J. Am. Chem. Soc. 2017, 139, 3340–3343.
DOI 10.1021/jacs.7b00049
Highlights 化学工業日報 日経産業新聞 Phys.org  c2W ScienceDaily  Chem-Station
Highlights Most Read Article (March, 2017)
Detail Decarbonylative Diaryl Ether Synthesis by Pd and Ni Catalysis

92. Catalytic α-Arylation of Ketones with Heteroaromatic Esters

Isshiki, R.; Takise, R.; Itami, K.; Muto, K.; Yamaguchi, J.
Synlett 2017, 28, 2599–2603.(Invited contribution)
DOI10.1055/s-0036-1589120
Detail ヘテロ芳香環エステルとケトンのα-アリール化反応

94. Decarbonylative C–P Bond Formation using Aromatic Esters and Organophosphorus Compounds

Isshiki, R.; Muto, K.; Yamaguchi, J.
Org. Lett. 2018, 20, 1150-1153.
DOI 10.1021/acs.orglett.8b00080
Detail 脱カルボニル化でC-P結合をつくる

96. Decarbonylative Aryl Thioether Synthesis by Ni Catalysis
 

Ishitobi, K.; Isshiki, R.; Asahara, K. K.; Lim, C.; Muto, K.; Yamaguchi, J.
Chem. Lett. 2018, 47, 756-759.
DOI 10.1246/cl.180226
Detail チオエステルからチオエーテルをつくる

97.Decarbonylative Coupling Reaction of Aromatic Esters

Isshiki, R.; Okita, T; Muto, K.; Yamaguchi, J.
J. Synth. Org. Chem. Jpn. 2018, 300-314.
DOI 10.5059/yukigoseikyokaishi.76.300
Detail 芳香族エステルの脱カルボニル型カップリング反応

98. Pd‐Catalyzed Decarbonylative C‐H Coupling of Azoles and Aromatic Esters

Matsushita, K.; Takise, R.; Hisada, T.; Suzuki, S.; Isshiki, R.; Itami, K.; Muto, K.; Yamaguchi, J.
Chem Asian. J. 2018, 13, 2393-2396.
DOI 10.1002/asia.201800478
Highlights Invitation to Contribute to a Special Issue: Homogeneous Catalysis from Young Investigators in Asia
Detail パラジウム触媒を用いた芳香族エステルの脱カルボニル型C–Hカップリング

101. Dibenzofuran Synthesis: Decarbonylative Intramolecular C‐H Arylation of Aromatic Esters

Okita, T.; Komatsuda, M.; Saito, A. N,; Hisada, T.; Takahara, T. T.; Nakayama, K. P.; Isshiki, R.; Takise, R.; Muto, K.; Yamaguchi, J.
Asian J. Org. Chem. 2018, 7, 1358-1361.
DOI 10.1002/ajoc.201800207
Highlights Invitation to Contribute to a Special Issue: C–H Activation
Highlights the top 10% most downloaded papers between January 2018 and December 2019

112. Ester Transfer Reaction of Aromatic Esters with Haloarenes and Arenols by a Nickel Catalyst

Isshiki, R.; Inayama, N.; Muto, K.; Yamaguchi, J.
ACS Catal. 2020, 10, 3490-3494.
DOI 10.1021/acscatal.0c00291
ChemRxiv. 2020, preprint
DOI 10.26434/chemrxiv.11577816.v1
Highlights Most Read Article (March and April, 2020)
Highlights Highlighted in newspaper(Nikkeisangyoshinbun, Chemicadaily)

116.Catalytic Deoxygenative Coupling of Aromatic Esters with Organophosphorus Compounds

Kurosawa, M. B.; Isshiki, R.; Muto, K.; Yamaguchi, J.
J. Am. Chem. Soc. 2020, 142, 7386–7392.
DOI 10.1021/jacs.0c02839
ChemRxiv. 2020, preprint
DOI 10.26434/chemrxiv.11973585
Highlights Most Read Article (May, 2020)
Highlights Highlighted in newspaper(Chemicadaily)

117.Solvent Selection Scheme Using Machine Learning Based on Physicochemical Description of Solvent Molecules: Application to Cyclic Organometallic Reaction

Fujinami, M.; Maekawara, H.; Isshiki, R.; Seino, J.; Yamaguchi, J.; Nakai, H.
Bull. Chem. Soc. Jpn 2020, 93, 841–845.
DOI10.1246/bcsj.20200045

124. Decarbonylative Synthesis of Aryl Nitriles from Aromatic Esters and Organocyanides by a Nickel Catalyst

Iizumi, K.; Kurosawa, M. B.; Isshiki, R.; Muto, K.; Yamaguchi, J.
Synlett 2021,32, 1555–1559.
DOI10.1055/s-0040-1705943
Highlights Invited as Cluster: Modern Nickel-Catalyzed Reactions 

126. Ni-Catalyzed Aryl Sulfide Synthesis through an Aryl Exchange Reaction

Isshiki, R.; Kurosawa, M. B.; Muto, K.; Yamaguchi, J.
J. Am. Chem. Soc. 2021, 143, 10333–10340.
DOI 10.1021/jacs.1c04215
ChemRxiv. 2021, preprint
DOI 10.26434/chemrxiv.14462376
Highlights Most Read Article (July, 2021)
Highlights Highlighted in Nikkan Kogyo Shinbun

135. Decarbonylative Reductive Coupling of Aromatic Esters by Nickel and Palladium Catalyst

Peng, Y.; Isshiki, R.; Muto, K.; Yamaguchi, J.
Chem. Lett. 2022, 51, 749–753.
DOI 10.1246/cl.220214
ChemRxiv. 2022, preprint
DOI 10.26434/chemrxiv-2022-s0sxl

コメント

大北とともに脱カルボニル型カップリング反応の求核剤の探索から初め、ケトンのα-アリール化、C–P結合形成反応を発見。エーテル化、C–Hアリール化にも一役買った。そこから、アリール交換（結合交換）反応を発見。研究室の代表作の１つとなった。さらには、脱アシル型のカップリング反応へも展開。研究室で最も活躍した博士課程の１人となった。

TOP